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A retrospective cohort study was conducted in 544 adult patients with severe COVID-19 related illness

zam M, Lynch SV
5-MTHF then donates a methyl group to homocysteine to convert it to methionine

Among these factors, a prominent role is played by NF-kB, whose role in inflammation in severe acute respiratory syndrome (SARS) has been demonstrated in both SARS-CoV-infected cultured cells and mice [34]
