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The loss of GHK over time may lead to reduced healing, collagen production, and regeneration of tissues as we age

In addition, uric acids and lipid profiles, such as triglycerides, total cholesterol, high-density lipoprotein and low-density lipoprotein cholesterol levels, did not differ between the two groups (Supplementary Table 1)

In comparison, lipotropic injections are relatively low-risk, natural, and inexpensive , though their effects are more subtle and dependent on individual metabolic conditions

Therefore, the purpose of this scoping review is to characterize the current evidence base for peptide therapies relevant to musculoskeletal care, with emphasis on BPC-157, thymosin beta-4 derivatives, and related agents, and to define safety considerations and perioperative implications for orthopaedic surgical patients, including those undergoing TJA