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Description
Two of the three native cysteine residues in that domain were mutated (C620A and C629T), leaving a single cysteine C598 that could form a mixed disulfide at the sites of RSOH formation

Suzuki R, Fujiwara Y, Saito M, et al

Researchers investigate its role in neurobiology and circadian rhythm control

5.1.7.3 Dysregulation of antioxidant defense systems Proteomic analyses of CF cellular models and patient samples have revealed a complex dysregulation of antioxidant enzyme expression
