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Kidney function is associated with an altered protein composition of high-density lipoprotein

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The PPAR agonists rosiglitazone and pioglitazone were recently found to reduce the levels of 2-HG and H3K4me3 in the colon of mice with colitis and to regulate GSH and ROS levels in lamina propria lymphocytes by modulating GLS1/2-HG/H3K4me3 signaling in mouse models of colitis and asthma ( Table 1 )

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PubMed, Meydani, S

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Statistical analysis Sample sizes for single-nucleus transcriptomics and DREADD experiments were determined based on prior experience with similar paradigms 12,13

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