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The combination allows a maximized release of GH because they each have a different mechanism of action, working on different receptors
However, proper use of peptides, monitoring their effects, and consulting with a doctor are essential to ensure their safety and maximum effectiveness
Tirzepatide vs semaglutide 2.4 mg in non-diabetic obesity SURMOUNT-5 direct head-to-head, -20.2% vs -13.7% at 72 weeks: Aronne NEJM 2025
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