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Karki P, Malik S, Mallick B, et al (2016) Massive Hemolysis Causing Renal Failure in Acute Hepatitis E Infection

Animal experiments have confirmed that PHGDH knockdown or treatment with its specific inhibitors effectively suppresses the growth of AML xenografts without significant toxicity to normal hematopoietic stem cells (95)

Smits RM, et al

Additionally, oxidative stress plays a key role in bone deterioration, causing inflammation, angiogenesis and synovial proliferation [16]