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Description
This can happen through direct competitive or non-competitive inhibition or through mechanism-based inactivation (MBI) that is also known as suicide inhibition, in which the enzyme is altered irreversibly (Figure 2, it summarizes how this mechanistic work ultimately affects drug metabolism

1997;26:584592 Ramm GA, Ruddell RG

10.3389/fphar.2017.00606

Besides affecting facial muscles, the nerve affects tears, saliva, taste and a small bone in the middle of the ear
