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Yoritaka A, Hattori N, Uchida K, Tanaka M, Stadtman ER, Mizuno Y

A novel acetophenone compound can act as nucleophilic substitutes for cisplatin in platinum-cysteine thiolate site interactions which is responsible for cisplatin ototoxicity

GSH protects mitochondria via the glutathione-ascorbate cycle, also known as the Asada-Halliwell pathway [22], which is the main pathway to neutralize the hydrogen peroxide radicals created as a byproduct of normal metabolism

It suggested a non-linear dose-response relationship, indicating that a daily intake of 2000 mg (oral) of L-Carnitine could provide the maximum effect in reducing body weight among adults, particularly those with overweight or obesity
