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Up to 4 out of 10 patients who see a doctor for fatigue are ultimately discovered to have undiagnosed but treatable health problems

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Neth J Crit Care 18:2527 Yamamoto Y, Takahashi Y, Imai K et al (2013) Risk factors for hyperammonemia in pediatric patients with epilepsy

A pathway by which this occurs is suggested in a recent study by Hamdan et al., who found that ROS from human FF of patients with endometriosis damaged mouse oocyte DNA and triggered arrest of meiosis in MI via the DNA damage checkpoint (151)
