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Caffeic Acids role in mitigating polycystic ovary syndrome by countering apoptosis and ER stress triggered by oxidative stress

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Here, phenobarbital (PHB), which belongs to the barbiturate class of drugs, was selected as the typical representative of neurotoxins (Rubio et al., 2022), since PHB was not only abused but also often deliberately overdose for suicide or other purposes (resulting in acute and chronic intoxication) (Yanai et al., 1985

and canola, walnut, and soybean oils) is metabolized to stearidonic acid (SDA), then to eicosatetraenoic acid (ETA), and then to eicosapentaenoic acid (EPA