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These observations suggest that the actions of enhanced Ahcy increased the levels of both products in dwarf mice but that homocysteine was likely rapidly utilized via transsulfuration as evidenced by the elevated levels of downstream Cbs and Cth

doi: 10.1371/journal.pone.0006692

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XBP1-deficient T cells in mice enhance antitumor immunity, suggesting their therapeutic potential in targeting this pathway
