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doi: 10.3389/fmicb.2024.1319897 Received 11 October 2023 Accepted 18 November 2024 Published 02 December 2024 Volume 15 - 2024 Edited by Almagul Kushugulova, Nazarbayev University, Kazakhstan Reviewed by Li Zhang, Brown University, United States Zhanagul Khassenbekova, Kazakhstan Society of Human Microbiome Researchers, Kazakhstan Updates Copyright 2024 Tarantino, Cataldi and Citro

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In humans, intravenous infusion of PP (10 pmol/kg/min) (supra-physiological levels of PP) in ten healthy volunteers (men and women of normal body weight) caused a sustained decrease in both appetite and cumulative 24-hour energy intake by 25.3 +/- 5.8% (193)