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In fact, patients hospitalized for long periods tend to suffer from malnutrition and sarcopenia, mainly due to prolonged mechanical ventilation and immobility [38]

[DOI] [PMC free article] [PubMed] [Google Scholar] 48.Huang T., Zhang K., Sun L., Xue X., Zhang C., Shu Z., Mu N., Gu J., Zhang W., Wang Y., et al

Phase II enzymes play a major role in the biotransformation of xenobiotics and endogenous compounds to more easily excretable forms, as well as inactivating the metabolism of pharmacologically active substances

Without enough folate, cells can get damaged, and the body may rely more on glucose for energy instead of breaking down proteins and fats