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Inhibition of gene expression and production of iNOS and TNF-alpha in LPS-stimulated microglia by methanol extract of Phellodendri cortex

Xu X., Wang Y., Luo X., et al., A NonInvasive Strategy for Suppressing Asthmatic Airway Inflammation and Remodeling: Inhalation of Nebulized Hypoxic hUCMSCDerived Extracellular Vesicles, Frontiers in Immunology 14 (2023): 1150971

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Newly synthesized dopamine is sequestered in vesicles via active transport with the involvement of vesicular monoamine transporter 2 (VMAT2), which is a regulator of cytoplasmic levels of dopamine at physiological levels preventing ROS-induced oxidative stress
