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(2) Incidence and Severity Research: Several cohort studies show that the incidence of high altitude illnesses (such as Acute Mountain Sickness, Chronic Mountain Sickness, High Altitude Pulmonary Edema, and High Altitude Cerebral Edema) increases with rising altitude and exhibits significant individual variability ( (3) Exploration of Influencing Factors: Researchers have thoroughly investigated and statistically analyzed a variety of potential factors affecting the occurrence and progression of high altitude illnesses

Genomic DNA was isolated from Burkholderia with the PureLink Genomic DNA Mini Kit (Invitrogen) or by standard isopropanol precipitation and solubilized in 10 mM Tris-HCl pH 8.5