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Using two independent inflammatory versus toxic models of demyelination and remyelination, Voskuhl and colleagues showed that genes involved in cholesterol synthesis were upregulated in oligodendrocytes during the remyelination phase
Because of lack of renal clearance, serum values rose to more than a hundredfold from 422 pmol/L on average to 54 000 pmol/L, with 67 000 pmol/L as highest value, without side-effects

[DOI] [PubMed] [Google Scholar] 66.Singh J, Giri S

The main purpose of glucose metabolism is to generate lactate, which can store a vast amount of carbon, resulting in a reduction of carbon sources entering the TCA cycle and a continuous flow of intermediate TCA cycle products into the cytoplasm for the synthesis of biological macromolecules, such as lipids, nucleotides and proteins
