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This is a theoretical carcinogenic concern, not an established finding, but its the category where caution is most warranted

These changes are related to the sodium-retaining properties of GH and IGF-1 via ENaC in the renal distal tubules ( vide supra ) and can be reversed if patients undergo effective treatment of the GH-producing tumor [100]

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Furthermore, THP-1 cells exposed with bacterial-derived lipopolysaccharide (LPS) exhibited an additive effect on the tyrosine phosphorylation of extracellular signal-regulated kinases 1/2 when co-treated with Epitalon