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In both postmortem samples and preclinical models from diabetic patients, retinal Nrf2 DNA-binding activity was found to be reduced [26,343,369]
The PDP regulatory subunit is encoded by the PDPR gene which is located on chromosome 16q22.1 and is composed of 23 exons that generate four alternatively spliced mRNAs that collectively encode three distinct precursor proteins
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doi: 10.3389/fpsyt.2022.880568 41 DiGiulioDB
