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Description
However, GLP-1 is rapidly degraded by the enzyme dipeptidyl peptidase IV (DPP IV), making it unattractive as a therapeutic agent
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Furthermore, obesity and metabolic syndrome (MetS) also appear to be risk factors for the occurrence of PD through the same mechanism, namely systemic inflammation, insulin and leptin resistance, blood-brain barrier disruption, and altered brain metabolism (Neto et al., 2023
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