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Stage 4 is the most severe stage of B12 deficiency
Khnel, J., Syrek, C
If you add exactly 2 mL of water and the powder adds 0.1 mL of volume, your actual total volume is 2.1 mL, making the true concentration slightly lower than calculated
(2021) Effects of vitamin B12 supplementation on cognitive function, depressive symptoms, and fatigue: a systematic review, meta-analysis, and meta-regression
