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Mice on a high-fat diet showed increased glucose uptake in skeletal muscle and reduced lipid deposition in the liver after supplementation with creatine [32,33]

They certainly expected this criteria to be immutable though

As the importance of subcellular metabolite transporters in controlling tumor initiation is poorly understood, it would be interesting to determine whether overexpression or knockout of these transporters is involved in tumorigenesis, metastasis, and immune modulation

Outcomes from massive paracetamol overdose: a retrospective observational study
