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Undoubtedly, drug-induced nephrotoxicity is a major cause of renal impairments and a potential impediment to the research and development of drugs, requiring more reliable and early diagnosis to avoid potentially fatal chronic conditions

She proposed that persistence characterizes a bacterial subpopulation (typically less than 1%) to survive antibiotic exposure, while tolerance describes the same ability but pertains an entire bacterial population 85,137 (Fig

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doi: 10.1079/PNS2002166 64 ZhangHLiuXLiBZhangYGaoHZhaoXet al