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It has been used extensively to remedy ischemic heart disease and has been shown to have good clinical efficacy (Yang et al., 2016
10.1094/PHYTO.1999.89.8.673 72 IshiharaT.SakuraiN.SekineK
More interestingly, several studies support that ferroptosis and necroptosis are alternative pathways, such that resistance to one pathway sensitizes cells to death via the other pathway
Purification of the nitrone by activated charcoal or by column chromatography also proved difficult as the end reaction products exhibited comparable polarity
