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The competition between NA methylation and NAD + salvage indicates that NNMT might limit fuel oxidation and promote fat storage, because if the activity or expression of NNMT is high, then, NA might not be salvageable, thus limiting the NAD + -dependent processes [16]
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doi: 10.1038/ni.1937 87 YaoYXuX-HJinL
Metabolism of such oxo-aldehydes through the glyoxalase system involves conjugation to GSH, catalyzed by glyoxalase 1
