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Glutathiones antioxidant properties help combat oxidative stress, which contributes to aging

doi:10.1146/annurev.bi.45.070176.003015 17

A three-year randomized, double-blind, placebo-controlled trial in 818 older adults (aged 50-70 years) with elevated homocysteine levels but normal serum vitamin B 12 levels found that folic acid supplementation (800 g/day) lowered homocysteine levels and improved measures of memory performance (115)

Rhee and Bae, 2015), resulting in the degradation of LC3SQSTM1Keap1 aggregates by selective autophagy
