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Currently, treatments based on copper metabolism in cardiovascular disease can encompass a wide range of options, including copper chelating agents [such as triethylenetetramine (TETA), tetrathiomolybdate (TTM) and disodium ethylene diamine tetraacetic acid (EDTA)], small-molecule inhibitors of copper chaperone proteins (such as DCAL50), copper ion carriers and natural antidote agents (Table II)

Conclusion The burden of cancer measured by incidence and mortality rates have improved in Korea, with the exception of a few particular cancers that are associated with increasing incidence or mortality rates

This happens because of a lack of vitamin B12, which is key for the nervous system

Mechanistically, PRLMs reshape the inflammatory milieu by suppressing T-cell activation and infiltration in both the peripheral and central immune compartments while promoting anti-inflammatory phenotypes in macrophages and resident microglia [267]