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In 2019, it was estimated that 1,401,931 cases of oral cancer were diagnosed worldwide (Global Health Data Exchange 2022)

This enzyme regulates the oxidation state of protein methionine residues but based on its turnover rates (Tarrago et al., 2009), it is unlikely to make an appreciable contribution to increases in GSSG during oxidative stress

Indeed, in Hgf- or Met-null mice, the development of liver is severely impaired and the placental labyrinth is hypomorphic, leading to death in utero (Schmidt et al., 1995

it may prevent the use of systemic antibiotics and thereby prevent antimicrobial resistance and improves patient compliance/adherence to the therapy and, most importantly, compared to systemic therapy, the risk of medication toxicity is significantly lower