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Using in vivo electrophysiology and behavioral assays in mice, we found that: Psilocybin inhibited serotonin neuron firing via 5-HT2A receptors and induced the head twitch response (HTR), consistent with psychedelic-like activity

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Bath sonication is preferred as probe sonication might release heavy metals like titanium in the dispersion [18]

Within the context of purine nucleotide biosynthesis, fumarate is generated by the actions of adenylosuccinate lyase in the conversion of succinylaminoimidazole carboxamide ribotide (SAICAR) to 5-aminoimidazole-4-carboxamide ribotide (AICAR) and in the conversion of adenylosuccinate to AMP