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CHB is also characterized by T-cell exhaustion, which is worsened by alcohol and includes up-regulation of PD-1, CTLA-4, and TIM-3 (66), impaired mitochondrial function in T cells (23, 67), and impaired antigen-presenting function of dendritic and Kupffer cells (6870)

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[DOI] [PubMed] [Google Scholar] 91.Jurado J., Prieto-lamo M.J., Madrid-Rsquez J., Pueyo C
