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These genes were classified by Lemaire (2004) into subfamilies depending on predicted active site motifs, with additional GRX or similar sequences described more recently (Navrot et al., 2006

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Hence, the present review briefly summarizes the functions of ROS as signaling molecules in order to discuss their roles in cancer development and progression

Third, each LDSF may influence multiple targets within the cardiovascular system and show pleiotropic effects through different molecular mechanisms