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Although some patients develop a mild rash to allopurinol that remains mild over time, or respond to antihistamines, continuing the allopurinol despite a rash is not advised, since the rash can worsen unpredictably

At the molecular level, MSM acts as a vital "sulfur donor." This means it safely delivers elemental sulfur to the body's metabolic pathways, where it is utilized to synthesize essential sulfur-containing amino acids like methionine and cysteine
