glutathione gsh deficiency alters the vitamin D-metabolizing enzymes CYP27B1 and CYP24A1 in human renal proximal tubule epithelial cells and kidney of HFD-fed mice Role of GSH in carcinogenesis
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Wu X, Cai J, Li X

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Because of the many critical roles TGF- family members play in normal development and tissue homeostasis, potent inhibition of all TGF- signaling would likely lead to unacceptable toxicity
