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Description
Mutations in the HSD11B2 gene are associated with an apparent mineralocorticoid excess-induced hypertension due to the lack of ability to inactivate cortisol

Pathogenesis An increased number of melanocytes within the basal layer of the epidermis leads to an increased production of melanin, resulting in hyperpigmented macules

Volanesorsen to treat severe hypertriglyceridaemia: A pooled analysis of randomized controlled trials

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