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Description
This signaling pathway is essential for the hypertrophic effects of IGF-1.23 Notably, IGF-1 has also been shown to promote intracellular lipid accumulation in mesangial cells, a phenotype similar to foam cells, which leads to reduced contractility in response to angiotensin-II.24,25 Furthermore, kidney samples from patients with advanced CKD and mouse models with renal fibrosis have defective fatty acid oxidation and higher lipid accumulation than controls without fibrosis

This product may be used in a hospital, a clinic, and a licensed medical facility

Packaging: Since copper peptides are sensitive to light and oxidation, high-quality products are packaged in opaque or dark containers with airtight seals to protect them from these elements
10.3390/cells9010143 72
