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doi:10.1016/j.amjoto.2021.103151
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The double-blind multicenter phase 3 trials STEP 1, 3, 4, 5 were conducted in adults (mean age 46.247.3 years), mostly females, with obesity or overweight with 1 weight-related complication (mean BMI 37.838.4 kg/m 2 ) and aimed to demonstrate the superiority of semaglutide 2.4 mg over placebo in BW lowering at 68 or 104 24 weeks as an adjunct to diet and physical activity 23
Zone 2 Cardiovascular Exercise: Gentle, steady-state cardio (like brisk walking or light cycling) is proven to stimulate mitochondrial biogenesisthe creation of brand new mitochondria
