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Intrahepatic CPSS generally has poorer prognosis

[DOI] [PubMed] [Google Scholar] 128.Montano L., Baldini G.M., Piscopo M., Liguori G., Lombardi R., Ricciardi M., Esposito G., Pinto G., Fontanarosa C., Spinelli M., et al
Additionally, GSVA revealed strong downregulation of inflammation-related pathways such as interferon (IFN), IL6, IL12, and transforming growth factor (TGF ) signaling in both macrophage clusters

This death of effector T cells is essential for maintaining immune homeostasis and preventing autoimmune responses
