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In contrast, the erastin-induced oxidative stress and cell death could be prevented in HT-1080 and other cancer cell lines by Trolox (a vitamin E analog), the iron chelator deferoxamine (DFO), the MEK inhibitor U0126, and the glutathione peroxidase mimetic ebselen
While the body can produce some antioxidants, many need to be consumed as part of a diet or supplementation, such as Vitamins A, C, E, lycopene and flavonoids
Lastly, we asked if LYSET is required for GNPT activity after its cleavage/activation
Blood 100 , 10261030 (2002)
