kb glutathione review 2018 Catabolic rewiring in cancer impacts dietary interventions Therapeutic effects and molecular mechanisms
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Endocrinology 164, bqad099

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Thus, when glutamine is bound in the active site, the tunnel can transiently open through altered interactions between Arg1263, Ser1052, and Asp657, along with a sidechain rotation to break a hydrogen bond between His296 and Thr310 (Figure 4E)

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