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doi: 10.1038/nm836 34 LutzHUStammlerPBianchiVTrebRMHunzikerTBurgerRet al

Thioredoxin-1 protects against neutrophilic inflammation and emphysema progression in a mouse model of chronic obstructive pulmonary disease exacerbation
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For example, as a transcriptional coactivator, peroxisome proliferator-activated receptor coactivator 1 (PGC1) has been reported to be downregulated in TC cells, thereby inhibiting oxidative phosphorylation and inducing a glycolytic phenotype

Burk RF, Norsworthy BK, Hill KE, Motley AK, Byrne DW
