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it mediates the hypoxic induction of erythropoietin and coordinates erythropoietin and erythrocyte production with iron metabolism Peritubular renal interstitial fibroblast-like cells and pericytes synthesize erythropoietin in an oxygen-regulated and HIF-2-dependent manner

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The initial reaction rates at different concentrations of compound were used to determine EC 50 values, which were calculated with a four-parameter logistical model of log dose against percentage activation and were obtained from at least three sets of experiments

Diagnosis and management of attention-deficit/hyperactivity disorder in adults