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Description

Before examination, mice were anesthetized with an intraperitoneal injection of sodium pentobarbital (87.5 mg/kg) and the pupils were dilated with a mixed solution of 0.5% phenylephrine and 0.5% tropicamide

With age, collagen and elastin production decline, causing sagging and wrinkles

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Based on descriptions of more severe COVID-19 in adult CF carriers, who have only one copy of wildtype CFTR , we suggest that this model-based conclusion may be consistent with otherwise normal patient-based experience