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miRNAs are short pieces of RNA ( ~ 22 nucleotides ) that affects the epigenome through binding to target mRNAs controlling the expression of key regulators such as DMNTs and histone deacetylases

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After embedding, the paraffin block was sectioned at 15-m thickness using a rotary microtome (order number: RM2155, Leica Microsystems, Wetzlar, Germany)
