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Genetic defects affecting the biosynthesis and/or structure of the fibrillar collagens have been implicated in the classic (type V collagen, OMIM 130000), vascular (type III collagen, OMIM 130050), arthrochalasia (type I collagen, OMIM 130060), kyphoscoliosis (lysylhydroxylase 1, OMIM 225400), and dermatosparaxis (ADAMTS-2, OMIM 225410) forms of EDS

Certain blood disorders, such as leukemias, are not assigned a stage because they travel throughout the body in the bloodstream

[DOI] [PMC free article] [PubMed] [Google Scholar] 106.Hosseinabadi F., Jenabi M., Ghafarizadeh A.A., Yazdanikhah S

Based on studies involving APP/PS1 transgenic mice, FGF-21 has been shown to reduce A plaque deposition and suppress pathological tau hyperphosphorylation in AD model mice by modulating monocarboxylate transporter-dependent metabolic pathways [93]