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doi: 10.1016/J.TOX.2004.01.008 123 de MarcoRPoliAFerrariMAccordiniSGiammancoGBugianiMet al

Given that M-cells have well-accepted BT capability and overlie intestinal lymphoid aggregates, M-cell mediated BT is one plausible mechanistic explanation [16, 17]

Their therapeutic strategy uses exon skipping. You may recall that DNA and the related chemical messenger RNA are read by cellular machinery in three-letter words. Typically, the mutations that cause DMD lead to a so-called frameshift, where the words for the rest of the gene after the mutation start and stop in the wrong places

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