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BPC-157 significantly enhances ERK1/2 phosphorylation in a dose-dependent manner, activating downstream targets including transcription factors c-Fos, c-Jun, and Egr-1

However, they are further subdivided into smaller groups based on their bioactivity (enzymatic and non-enzymatic antioxidants), solubility (water-soluble and fat-soluble antioxidants), and size (small molecule and large molecule antioxidants) (Fig

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More studies are required to develop alternative strategies to alleviate oxidative stress and replenish glutathione levels in the lens center
