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The goal must evolve from merely suppressing pain to actively rectifying the dysregulated neural, immune, and endocrine processes that sustain it

Bromocriptine, the first dopamine receptor agonist, was originally made available in the 1970s, and has since grown in importance as a treatment for Parkinson's disease's motor symptoms

Animal studies demonstrate reduced lipid peroxidation in retinal tissue

As used herein, "conditions which allow alkylation of the sulfhydryl group of GSH with the maleimide" typically require that the maleimide (such as NEM) is (initially) present at a concentration of at least 0.0001 mM, preferably at least 0.001 mM, more preferably at least 0.01 mM, even more preferably at least 0.1 mM, yet even more preferably at least 1 mM or even at least 2 mM