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This unified metabolic strategy provides a pathway for symptom improvement in complex cases where traditional psychiatric treatments fall short

Inhibitors of BET proteins, including JQ1, are considered promising anticancer drug seeds, and BET protein degraders are more potent than inhibitors in cancer cell death and antiproliferation in both cell and mouse models 7

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Therefore, in-depth research into the relationships among NRF2, PTMs, and epigenetic modifications, as well as their roles in regulating NRF2 function, is crucial for elucidating the molecular mechanisms governing cellular redox homeostasis