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In addition to the hormonal and metabolic dysfunctions commonly associated with POF, genetic factors also play a significant role in its pathogenesis

Elsevier, pp 613640 Mangione CM, Barry MJ, Nicholson WK, Cabana M et al (2022) Vitamin, mineral, and multivitamin supplementation to prevent cardiovascular disease and cancer: US preventive services task force recommendation statement

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There may also be more proven, conventional treatments to help you achieve the same goals with less risk
