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EGEMS (Wash DC)

Both host human chromosomes 5 and 20, are involved in tumor genetic changes, but neither of them nor the corresponding mouse loci of the vitamin C transporter genes (located on chromosome 18 and 2, respectively) are involved in osteoporosis or other bone defects [142]

The term specific binding, specifically binds to, or specific for a particular polypeptide or an epitope on a particular polypeptide target can be exhibited, for example, by a molecule (e.g., an antibody) having a dissociation constant (K d ) for the target of at least about 10 -4 M, at least about 10 -5 M, at least about 10 -6 M, at least about 10 -7 M, at least about 10 -8 M, at least about 10 -9 M, at least about 10 -10 M, at least about 10 -11 M, or at least about 10 -12 M