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As a person with an existing autoimmune condition, I understand
Cystathionine synthase and cystathioninase require P5P as a cofactor, and the committed first step in the degradation of homocysteine, cystathionine synthase, also requires serine, a downstream metabolite of betaine (Figure 54-6)
Chem 4 , 19371951 (2018)
These findings suggest that the initial GSH concentration has a limited effect on antioxidant capacity and the level of [ROS] in RP retinas
